Best First-Round Picks, 1999-2008

Edgerrin James: 4th Pick 1999: James' 12,121 career rushing yards is best among active running backs and 11th all-time, 122 yards behind Marcus Allen at No. 10.

Ed Reed: 24th Pick  2002: In one of the more loaded picks, Reed wins by virtue of being one of the best ever to play safety. A testament of how widely respected he is, Reed was the only unanimous selection to the 2008 All-Pro team.

Jon Beason : 25th Pick 2007: One of the game's best young linebackers, Beason led the Panthers in tackles each of his first two seasons and earned All-Pro honors in 2008.

Reggie Wayne: 30th Pick 2001: Making a name for himself as Peyton Manning's No. 2 receiver early in his career, Wayne has now solidified himself as the Colts' No. 1. He has started every game since 2003 and has five straight 1,000-yard seasons.